Location
1.5 thumb widths lateral to the du mai at the level of the lower border of the spinous process of the 12th thoracic vertebra.
Cautions
Avoid deep perpendicular needling.
Indications
Conditions for which BL21 is listed as indicated. An indication list is a reference index, not a prescription – see the protocols below for sourced treatments.
Appetite Strong Unable To EatPoor AppetiteBenefit Descend RebellionBenefit DigestionBenefit Regulate Jiao MiddleBenefit Regulate StomachStomach RumblingCold StomachContraction Back(infant) Nutrition DeficiencyInfantile Nutrition DeficiencyDescend RebellionDiarrheaTurmoil DisorderAbdominal BloatingStomach BloatingEyesight / Vision DimDim VisionFibroids / Masses Ji Abdomen Long TermFibroids Masses Ji Abdomen Long TermAbdominal FullnessCostal Lateral FullnessEpigastrium FullnessTendon Ligament Contraction StiffnessImmobility Tendon / Ligament ContractionJaundiceMalariaEdemaBack PainChest PainUpper Stomach PainRectal ProlapseReflux StomachRegulate Jiao MiddleRegulate StomachUndigested Food in StoolTympanites / Drum BellyTympanites Drum BellyVomitingVomiting FluidVomiting Milk (infant)Vomiting Milk InfantileVomiting Previous Day's FoodWeight Low Despite Appetite
Protocols using BL21
The 50 best-sourced of 107, ranked by strength of evidence. The count above is the full figure.
- Nausea, Bloating, Heartburn, Dyspepsia Functional, Abdominal Pain Epigastric, Early Satiety, Postprandial Fullness – BL21, CV12 (doi:10.1186/1745-6215-10-75 ↗)
- Nausea, Bloating, Dyspepsia Functional – ST34, ST36, BL21, CV12 (doi:10.1155/2012/543943 ↗)
- Anxiety Procedural, Procedural Pain – BL21, BL22, BL23, BL52, GB25 (doi:10.1097/j.pain.0000000000000734 ↗)
- Epigastric Pain, Dyspepsia Functional, Burning Epigastric – ST36, ST44, SP09, BL20, BL21, PC06, LV03, LV13, LV14, CV12, CV17 (doi:10.1186/s13063-017-1845-3 ↗)
- Hyperglycemia, Prediabetes, Impaired Glucose Tolerance – LI04, ST36, ST37, ST39, ST40, SP06, SP09, BL18, BL20, BL21, LV03, LV13, LV14, CV12, GV09 (doi:10.1186/s13063-017-2014-4 ↗)
- Epigastric Pain, Dyspepsia Functional, Postprandial Fullness, Satiety Early, Nausea Postprandial – ST34, ST36, ST40, ST42, BL20, BL21, PC06, CV12 (doi:10.1136/bmjopen-2017-018430 ↗)
- Overweight, Obesity Simple, Bmi Elevated – LI04, LI11, ST21, ST24, ST25, ST26, ST27, ST28, ST32, ST34, ST36, ST37, ST39, ST40, ST44, SP04, SP06, SP09, SP14, SP15, SP16, BL20, BL21, TB06, GB26, LV13, CV04, CV06, CV07, CV09, CV10, CV12, CV13 (doi:10.1155/2020/2367610 ↗)
- Diarrhea, Abdominal Pain, Ulcerative Colitis, Blood In Stool – ST25, ST36, SP04, BL20, BL21, BL23, BL25, KD03, CV04, CV12 (doi:10.1186/s12906-020-03101-4 ↗)
- Diarrhea, Abdominal Pain, Ulcerative Colitis, Blood In Stool – ST25, ST36, SP04, BL16, BL20, BL21, BL22, BL25, KD03, CV04, GV02, GV06 (doi:10.1186/s12906-020-03101-4 ↗)
- Cancer Gastric, Cancer Advanced, Post-chemotherapy – LU10, ST16, ST36, SP18, BL21, BL23, BL43, GB42, CV12 (doi:10.1155/2020/8274021 ↗)
- Abdominal Pain, Postoperative Pain, Post-Operative Nausea, Post-Operative Vomiting, Abdominal Bloating – LI04, ST36, ST37, BL21, BL27, PC06 (doi:10.2147/CMAR.S292325 ↗)
- Vomiting, Nausea, Abdominal Pain, Abdominal Bloating, Postprandial Fullness, Satiety Early, Gastroparesis Diabetic, Loss Of Appetite – ST21, ST25, ST36, SP06, BL18, BL20, BL21, BL23, PC06, CV12 (doi:10.1155/2021/6649331 ↗)
- Obesity, Obesity Abdominal, Overweight, Waist Circumference Elevated – LI11, ST24, ST25, ST36, ST40, BL20, BL21, TB06, CV09, CV12 (doi:10.1155/2022/4780019 ↗)
- Epigastric Pain, Dyspepsia Functional, Satiety Early, Burning Epigastric, Epigastric Postprandial Bloating – BL21, CV12 (doi:10.1155/2022/4824575 ↗)
- Loss of Appetite, Chemotherapy Nausea, Fatigue Cancer, Anorexia Cancer-associated – LI04, LI11, ST25, ST36, ST37, SP06, SP09, HT07, BL20, BL21, BL23, PC06, CV04, CV06, CV12, GV20 (doi:10.1155/2022/4251458 ↗)
- Headache, Sore Throat, Joint Pain, Muscle Pain, Fatigue Chronic, Sleep Unrefreshing, Memory Impaired, Fatigue Post-exertional, Cold Intolerance, Concentration Impaired, Yang Deficiency Spleen-kidney, Lumbar Weakness – BL11, BL13, BL14, BL15, BL17, BL18, BL19, BL20, BL21, BL22, BL23, BL25, GV02, GV03, GV04, GV05, GV06, GV07, GV08, GV09, GV10, GV11, GV12, GV13, GV14 (doi:10.1186/s12967-023-04250-z ↗)
- Anorectal Pain, Rectal Pain, Anorectal Bloating, Defecation Disorder – ST36, BL20, BL21, BL23, BL34, BL35, BL57, GB26, CV04, CV06, CV12, GV01, GV20 (doi:10.1097/MD.0000000000035462 ↗)
- Proteinuria, Nephropathy Diabetic, Renal Function Impaired, Hemorheology Abnormal – SP06, BL13, BL21, BL23, KD03 (doi:10.13702/j.1000-0607.20210036 ↗)
- Fatigue, Constipation, Insomnia, Weight Loss, Eating Disorder Arfid, Food Avoidance, Abdominal Bloating, Taste Disturbance, Tongue Pain – LI04, ST19, ST20, ST24, ST25, ST36, ST40, SP04, SP06, HT07, SI03, BL15, BL19, BL20, BL21, BL22, KD06, PC06, GV20 (doi:10.7759/cureus.61912 ↗)
- Parkinson's Disease, Bradykinesia, Rigidity Muscular, Posture Forward, Posture Lateral Trunk Bending, Dysphasia, Micrographia, Pisa Syndrome – ST40, SI03, BL21, BL62, KD06, LV03, LV08, LV13, GV20 (doi:10.7759/cureus.70860 ↗)
- Obesity, Appetite Excessive, Overweight, Appetite Increased – ST25, BL20, BL21, BL25, LV13, CV12 (doi:10.2147/DMSO.S487877 ↗)
- Anxiety, Fibromyalgia, Whole-body Pain, Mood Depressive – ST25, ST27, ST36, SP04, SP06, HT07, SI03, BL16, BL18, BL19, BL20, BL21, BL23, BL62, KD03, KD06, TB05, LV03, LV08 (doi:10.7759/cureus.74385 ↗)
- Knee Pain, Osteoarthritis Knee, Stiffness Knee – ST34, BL19, BL21, BL23, BL25, BL27, BL40 (doi:10.1186/s12906-025-04891-1 ↗)
- Airway Hyperresponsiveness, Asthma Intermittent, Asthma Mild – LU01, LU05, LU07, LU09, LU11, LI04, LI06, LI20, ST13, ST25, ST36, ST40, ST44, SP03, SP06, SP09, SP10, HT03, HT05, HT07, SI03, BL13, BL17, BL18, BL20, BL21, BL23, KD03, KD06, KD08, KD27, PC06, TB05, TB15, GB03, GB34, GB40, GB41, LV02, LV03, LV08, LV13, CV04, CV06, CV09, CV17, CV21, GV04, GV13 (doi:10.1186/s13052-015-0155-1 ↗)
- Hyperglycemia, Insulin Resistance, Type 2 Diabetes – LI04, LI11, ST36, SP06, SP09, SP10, BL13, BL17, BL20, BL21, BL22, BL23, BL52, KD03, CV04, CV06, CV12 (doi:10.3892/etm.2017.4379 ↗)
- Lactation Insufficiency, Breastfeeding Postpartum – ST18, ST36, SP06, SP10, SI01, BL20, BL21, PC06, LV03, LV14, CV06, CV17 (doi:10.22038/ijp.2020.54458.4305 ↗)
- Lactation Insufficiency, Breastfeeding Postpartum – ST18, ST36, SI01, BL18, BL20, BL21, LV03, LV14, CV12, CV17, GV14 (doi:10.22038/ijp.2020.54458.4305 ↗)
- Lactation Insufficiency, Breastfeeding Postpartum – LU01, LI04, ST17, ST18, SP20, SI01, BL17, BL18, BL20, BL21, GB21, CV17 (doi:10.22038/ijp.2020.54458.4305 ↗)
- Lactation Insufficiency, Breastfeeding Postpartum – LI04, ST11, ST17, SP20, SI01, BL17, BL18, BL20, BL21, GB21, CV16, CV17 (doi:10.22038/ijp.2020.54458.4305 ↗)
- Vomiting, Nausea, Chemotherapy Nausea, Stomach Yin Deficiency – ST36, SP04, BL21, KD06, PC06, CV04, CV12 (doi:10.1177/2164956119870444 ↗)
- Cancer Pain, Constipation Opioid-induced – BL18, BL19, BL20, BL21, CV12 (doi:10.3390/jcm12155083 ↗)
- Nasal Congestion, Allergic Rhinitis, Sneezing, Nasal Itching, Rhinorrhea Clear – ST36, BL12, BL20, BL21 (doi:10.1016/j.heliyon.2024.e29262 ↗)
- Hypogalactia, Breastfeeding Insufficiency, Lactation Postpartum – ST18, ST36, SP06, SP10, SI01, BL20, BL21, PC06, LV03, LV14, CV06, CV17 (doi:10.1186/s13643-025-02773-8 ↗)
- Hypogalactia, Breastfeeding Insufficiency, Lactation Postpartum – ST18, SI01, BL18, BL20, BL21, CV17, GV14 (doi:10.1186/s13643-025-02773-8 ↗)
- Hypogalactia, Breastfeeding Insufficiency, Lactation Postpartum – LU01, LI04, ST17, ST18, SP20, SI01, BL17, BL18, BL20, BL21, GB21, CV17 (doi:10.1186/s13643-025-02773-8 ↗)
- Hypogalactia, Breastfeeding Insufficiency, Lactation Postpartum – LI04, ST11, ST17, SP20, SI01, BL17, BL18, BL20, BL21, GB21, CV16, CV17 (doi:10.1186/s13643-025-02773-8 ↗)
- Abdominal Distension, Gastrointestinal Dysfunction, Constipation Postoperative – ST25, ST36, BL20, BL21, BL23, BL25, TB06, CV04, CV06, CV12, GV01 (doi:10.1136/bmjopen-2025-108309 ↗)
- Heartburn, Regurgitation, Reflux Gastroesophageal – ST36, BL21, CV12 (doi:10.13181/mji.v28i3.1850 ↗)
- Nausea, Bloating, Epigastric Pain, Dyspepsia Functional – ST25, ST36, ST44, SP04, SP09, BL20, BL21, PC06, LV03, CV12 (doi:10.1016/j.dcmed.2024.01.001 ↗)
- Epigastric Pain – ST36, SP04, BL20, BL21, PC06, CV12, CV13 (doi:10.13703/j.0255-2930.20240904-k0002 ↗)
- Insomnia, Speech Slurred, Dysphagia, Lower Limb Weakness, Breathlessness, Nasal Regurgitation, Ptosis Eye Left, Weight Loss Gradual, Fatigue Generalized – LI04, SP03, BL20, BL21, GB20, GV20 (doi:10.13045/jar.24.0052 ↗)
- Gastric Mucosal Injury Stress-induced – ST36, BL20, BL21, CV12 (doi:10.13193/j.issn.1673-7717.2015.09.005 ↗)
- Peptic Ulcer, Epigastric Pain – ST36, BL20, BL21, CV12 (doi:10.27294/d.cnki.gsxzc.2023.000054 ↗)
- Lumbar Pain, Lower Limb Pain, Lower Limb Numbness – ST26, SP11, BL21, GB26, GB27 (doi:10.13192/j.issn.1000-1719.2023.05.059 ↗)
- Spleen-qi Deficiency, Allergic Disease, Middle-qi Deficiency – BL20, BL21, LV13, CV12 (doi:10.13463/j.cnki.cczyy.2025.11.009 ↗)
- Intestinal Obstruction Postoperative Inflammatory Early – ST25, ST36, ST37, ST39, SP15, BL20, BL21, BL25, PC06, TB06, LV03, CV04, CV06, CV12 (doi:10.19613/j.cnki.1671-3141.2019.76.008 ↗)
- Stomach Pain, Gastric Pain – LU10, SP05, BL13, BL21 (doi:10.13457/j.cnki.jncm.2025.08.020 ↗)
- Gastric Ulcer, Mucosal Erosion – ST36, BL20, BL21 (doi:10.13703/j.0255-2930.1994.04.027 ↗)
- Epigastric Pain, Cold Spleen-stomach Deficiency – ST36, BL20, BL21, PC06, CV04, CV12 (doi:10.27127/d.cnki.ghlzu.2023.000698 ↗)
- Diarrhea, Digestive Disorder Soft Stool, Soft Stool – BL20, BL21 (doi:10.27327/d.cnki.gshnu.2025.001669 ↗)
Most often selected alongside BL21
How many sourced protocols in the index pair each point with BL21. Corpus frequency, not a combination to use.
- BL20Spleen Shu Point80 protocols
- ST36Leg Three Miles74 protocols
- CV12Stomach Centre51 protocols
- ST25Celestial Pivot37 protocols
- SP06Three Yin Intersection36 protocols
- PC06Inner Gate31 protocols
- CV04Original Qi Gate28 protocols
- LV03Great Surge28 protocols
- BL23Kidney Shu Point27 protocols
- BL18Liver Shu Point25 protocols
- LI04Junction Valley25 protocols
- CV06Sea Of Qi21 protocols
