XL05A Neixiyan (Medial Eye Of The Knee)

Location

When the knee is flexed, in the depression medial to the patellar ligament. The medial member of the Xiyan (EX-LE 5) pair; EX-LE 4 (Neixiyan) denotes this point alone.

Indications

Conditions for which XL05A is listed as indicated. An indication list is a reference index, not a prescription – see the protocols below for sourced treatments.

TCM actions

What classical sources say XL05A does in the terms of Chinese medicine theory. These describe the point, not a condition.

Protocols using XL05A

The 50 best-sourced of 114, ranked by strength of evidence. The count above is the full figure.

• Anxiety, Knee Problems, Anxiety Postoperative, Knee Postoperative Pain, Knee Postoperative Rehabilitation, Meniscectomy – LU05, ST35, GB34, XL05A (doi:10.13703/j.0255-2930.20221228-0002 ↗)
• Knee Pain, Osteoarthritis Knee, Stiffness Knee – ST35, SP06, SP10, KD03, GB33, LV08, XL05A (doi:10.1186/s12906-025-04985-w ↗)
• Knee Pain, Osteoarthritis Knee, Stiffness Knee – ST34, ST35, ST36, SP10, BL18, BL23, GB33, GB34, XL05A (doi:10.1186/s12984-025-01692-y ↗)
• Knee Pain, Osteoarthritis Knee, Stiffness Knee – ST34, ST35, ST36, SP09, SP10, BL40, GB34, XL05A (doi:10.1111/1756-185x.70398 ↗)
• Knee Pain, Osteoarthritis Knee, Stiffness Knee – ST34, ST35, ST36, SP09, SP10, GB34, XL05A (doi:10.13703/j.0255-2930.20250223-k0001 ↗)
• Knee Pain, Osteoarthritis Knee, Stiffness Knee – ST35, GB33, LV08, XL05A (doi:10.2196/84082 ↗)
• Knee Pain, Osteoarthritis Knee, Stiffness Knee – ST34, ST35, SP10, GB34, XL05A (doi:10.13703/j.0255-2930.20240627-0002 ↗)
• Knee Pain, Chronic Pain, Osteoarthritis Knee, Sensitization Central – ST35, SP10, XL02, XL05A (doi:10.13703/j.0255-2930.20250807-k0001 ↗)
• Knee Pain, Osteoarthritis Knee, Stiffness Knee, Postoperative Pain – ST31, ST32, ST34, ST35, ST36, SP09, SP10, BL24, BL25, BL40, GB29, GB30, GB34, LV08, LV09, XL02, XL05A (doi:10.2147/JPR.S453133 ↗)
• Knee Pain, Osteoarthritis Knee – ST34, ST35, ST36, SP10, XL02, XL05A (doi:10.13703/j.0255-2930.20200310-k0011 ↗)
• Knee Pain, Osteoarthritis Knee, Knee Problems, Joint Knee Pain – ST35, ST36, SP09, SP10, GB31, GB36, GB39, GB41, XL02, XL05A (doi:10.13703/j.0255-2930.20191212-0001 ↗)
• Diabetes, Leg Pain, Leg Numbness, Claudication Intermittent, Disease Arterial Lower-extremity – LI04, LI11, ST36, ST40, ST42, SP03, SP06, SP09, KD03, GB34, XL05A, XL05B, XL10A, XL10B, XL10C, XL10D, XL10E, XL10F, XL10G, XL10H (doi:10.12659/MSM.909733 ↗)
• Knee Pain, Swollen Knee, Osteoarthritis Knee, Stiffness Joint – ST34, ST35, ST36, SP09, SP10, GB34, XL05A (doi:10.3389/fneur.2022.1026441 ↗)
• Osteoarthritis Knee, Joint Knee Pain – ST35, GB33, GV03, XB08, XL05A (doi:10.2147/jpr.s571098 ↗)
• Dysphagia, Muscle Weakness, Amyotrophic Lateral Sclerosis – LI10, LI11, LI14, LI15, ST31, ST32, ST34, ST35, ST36, ST41, SP06, SP10, BL36, BL37, BL40, BL57, GB20, GB30, GB31, GV20, XL05A (doi:10.1097/md.0000000000033612 ↗)
• Osteoarthritis Knee – ST34, ST35, ST36, SP09, SP10, XL05A (doi:10.1371/journal.pone.0101973 ↗)
• Peripheral Artery Disease Lower Extremity – LI04, LI11, ST36, ST40, ST42, SP03, SP06, SP09, KD03, GB34, XL05A, XL05B, XL10A, XL10B, XL10C, XL10D, XL10E, XL10F, XL10G, XL10H (doi:10.12659/MSM.909733 ↗)
• Osteoarthritis Knee – ST34, ST35, SP10, GB34, XL05A (doi:10.13703/j.0255-2930.20200708-k0003 ↗)
• Knee Pain, Osteoarthritis Knee, Knee Osteoarthritis Problems – ST34, ST35, ST36, SP10, GB34, XL02, XL05A (doi:10.2147/JPR.S634945 ↗)
• Knee Pain, Osteoarthritis Knee – ST34, ST35, ST36, XL05A (doi:10.13703/j.0255-2930.20210901-k0008 ↗)
• Knee Pain, Osteoarthritis Knee, Stiffness Knee – ST36, GB39, XL02, XL05A (doi:10.10372/j.1000-0607.20210079 ↗)
• Knee Pain, Osteoarthritis Knee – ST34, ST35, ST36, SP09, SP10, KD10, GB33, GB34, XL05A, XL05B (doi:10.1097/MD.0000000000030385 ↗)
• Knee Pain, Osteoarthritis Knee – ST34, ST35, ST36, SP10, GB34, XL05A (doi:10.13702/j.1000-0607.20210745 ↗)
• Osteoarthritis Knee – ST34, SP09, SP10, GB34, XL02, XL05A, XL05B (doi:10.1002/iid3.70430 ↗)
• Osteoarthritis Knee – LI11, ST34, ST35, ST36, SP06, SP10, KD03, GB34, XL05A (doi:10.2147/jpr.s578343 ↗)
• Osteoarthritis Knee – ST35, ST36, CV04, XL05A (doi:10.13703/j.0255-2930.20220617-k0002 ↗)
• Osteoarthritis Knee – ST34, ST35, SP10, XL05A (doi:10.1186/s13018-021-02398-2 ↗)
• Knee Pain, Osteoarthritis Knee – ST35, XL05A (doi:10.1097/MD.0000000000034537 ↗)
• Knee Pain, Osteoarthritis Knee – ST34, ST35, ST36, SP09, SP10, BL40, GB34, XL05A (doi:10.2147/JPR.S445770 ↗)
• Knee Pain, Osteoarthritis Knee – LI11, ST34, ST35, ST36, SP09, SP10, BL40, GB34, XL05A (doi:10.2147/JPR.S445770 ↗)
• Knee Pain, Osteoarthritis Knee – ST35, ST36, BL11, KD01, GB39, XL05A, XL05B (doi:10.13702/j.1000-0607.20221256 ↗)
• Knee Pain, Osteoarthritis Knee – ST35, ST36, XL05A, XL05B (doi:10.13702/j.1000-0607.20221256 ↗)
• Knee Pain, Osteoarthritis Knee – ST34, ST35, SP09, SP10, GB34, XL05A (doi:10.1007/s40122-025-00713-x ↗)
• Knee Pain, Osteoarthritis Knee – ST35, XL05A (doi:10.1007/s40122-025-00713-x ↗)
• Knee Pain, Osteoarthritis Knee – ST34, SP09, SP10, GB34, GV03, XL05A, XL05B (doi:10.1007/s10067-025-07497-7 ↗)
• Osteoarthritis Knee – ST34, ST35, SP10, XL05A (doi:10.13703/j.0255-2930.20190422-0005 ↗)
• Osteoarthritis Knee – ST35, ST36, XL05A (doi:10.13703/j.0255-2930.20200205-k0003 ↗)
• Knee Pain, Osteoarthritis Knee – ST34, ST35, ST36, SP09, SP10, BL40, GB34, XL05A (doi:10.1111/1756-185x.70398 ↗)
• Knee Pain, Osteoarthritis Knee – ST34, ST35, SP09, SP10, GB34, XL02, XL05A (doi:10.1371/journal.pone.0353654 ↗)
• Osteoarthritis Knee – ST34, ST35, SP06, SP10, GB34, XL02, XL05A (doi:10.1016/j.wjam.2022.07.009 ↗)
• Knee Pain, Osteoarthritis Knee – ST34, ST35, SP10, XL05A (doi:10.1016/j.heliyon.2023.e20771 ↗)
• Knee Pain, Osteoarthritis Knee – ST34, ST35, SP10, XL05A (doi:10.1186/s13075-019-1899-6 ↗)
• Osteoarthritis Knee – ST34, ST35, SP10, GB34, XL05A (doi:10.1186/s13063-020-04508-7 ↗)
• Knee Pain, Osteoarthritis Knee – ST35, SP09, GB34, XL05A (doi:10.2147/jpr.s519308 ↗)
• Osteoarthritis Knee – ST34, ST35, ST36, SP09, SP10, XL05A (doi:10.1159/000447925 ↗)
• Osteoarthritis Knee – ST34, ST35, SP10, XL05A, XL05B (doi:10.1159/000447925 ↗)
• Osteoarthritis Knee – ST35, XL05A (doi:10.1159/000447925 ↗)
• Osteoarthritis Knee – ST35, ST36, SP09, SP10, GB34, XL05A (doi:10.3389/fmed.2026.1864999 ↗)
• Osteoarthritis Knee – ST35, GB33, LV08, XL05A, XL05B (doi:10.1155/2020/1686952 ↗)
• Osteoarthritis Knee – ST34, ST35, ST36, SP09, SP10, GB34, XL05A (doi:10.1155/2020/3563584 ↗)

Most often selected alongside XL05A

How many sourced protocols in the index pair each point with XL05A. Corpus frequency, not a combination to use.

• ST35Calf's Nose103 protocols
• GB34Yang Mound Spring66 protocols
• SP10Sea Of Blood65 protocols
• ST34Ridge Mound61 protocols
• ST36Leg Three Miles58 protocols
• SP09Yin Mound Spring53 protocols
• XL02Crane's Summit32 protocols
• XL05BLateral Eye Of The Knee15 protocols
• GB39Suspended Bell12 protocols
• SP06Three Yin Intersection12 protocols
• GB33Yang Knee Gate11 protocols
• BL40Middle Of The Crease9 protocols

Other points on the Extra Points: Lower limbs